Serum Cover Art

Serum (v0.1.6)

Simulation 14.29 GB v0.1.6 778 views

Game Overview

A poisoned island shrouded in unnatural fog makes survival feel like a race against a ticking clock. Serum is a first-person survival adventure where a life-sustaining injection keeps you alive, but every dose also becomes a gamble with dangerous consequences. Mutated wildlife, ruined facilities, and traces of a lost scientific project give the setting a bleak, tense atmosphere rather than a simple sandbox wilderness feel. The central mystery gradually pushes you beyond basic survival as you search for answers about the serum, the disaster, and a possible escape.

Moment-to-moment play revolves around scavenging materials, gathering biological samples, and returning to shelter before your dwindling supply runs out. Plants and creatures provide ingredients for experimental brews, allowing you to create temporary boosts for mobility, combat, resistance, and other useful abilities; managing their side effects matters as much as discovering powerful recipes. Crafting covers practical tools, defenses, traps, and weapons, while a safe-zone system lets you establish a more reliable source of the precious substance. Combat supports close-range clubs and spears alongside bows and throwable weapons, with upgrades and serum-infused modifications giving you better odds against the island’s increasingly dangerous monsters.

What separates Serum from more familiar crafting survival games is how its survival pressure feeds directly into its progression system. You are not merely collecting food and building a base; every expedition demands preparation, recipe knowledge, stamina management, and a plan for getting home alive. Unreal Engine 5 visuals give its different biomes and decaying research sites a sharp, atmospheric presentation, while the brewing system encourages experimentation instead of locking upgrades behind a straightforward skill tree. Players who enjoy the exploration and crafting of The Forest or Subnautica, but want a harsher timer-driven structure and more active combat, are likely to find plenty to like here.

Screenshots

Installation

  1. Select the Download button at the top of this page to open UploadHaven.
  2. On UploadHaven, wait for any countdown, then select Free Download. Optional: UploadHaven Pro for faster downloads.
  3. When complete, extract the archive to a Serum folder using 7-Zip.
  4. Open the extracted folder and start the game normally.
  5. For errors, check Setup Guide & Troubleshooting below. Keep your security software enabled.

System Requirements

  • Requires a 64-bit processor and operating system
  • OS: Windows 10 (x64)
  • Processor: Intel Core i5-8400 or AMD Ryzen 5 2600X
  • Memory: 12 GB RAM
  • Graphics: NVIDIA GeForce GTX 1070, 8 GB or AMD Radeon RX Vega 56, 8 GB or Intel Arc A750, 8 GB
  • DirectX: Version 11
  • Storage: 15 GB available space
  • Sound Card: DirectX compatible
  • Additional Notes: Low settings, 1080p @ 30 FPS. CPU must support at least the SSE3 instruction set. Does not require the AVX instruction set.
Last Updated
Status
Online
Looking for a newer update? Request an update
Skip the browser next time Browse, download, extract, and organize your games with the SteamUnlocked Launcher.
Get the Launcher

Setup Guide & Troubleshooting

How do I fix missing DLL errors for Serum (v0.1.6)?

After extracting Serum (v0.1.6), navigate to the _Redist or _CommonRedist folder inside the game directory and install DirectX, Vcredist, and any other dependencies included.

What should I do if the downloaded file is corrupted?

The full archive is 14.29 GB — make sure your download completed fully before extracting. Use 7-Zip to extract the files. If you still see a "file corrupted" error, re-download and try again.

Do I need to run the game as administrator?

Usually, no. Start the game normally from the extracted folder. If you see a permissions or save error, check that the folder is writable and follow the game's documented fix. Only grant administrator access when a trusted game's specific setup requires it.

How do I update my GPU drivers for this game?

Serum (v0.1.6) requires a NVIDIA GeForce GTX 1070, 8 GB or AMD Radeon RX Vega 56, 8 GB or Intel Arc A750, 8 GB or equivalent. Update your NVIDIA or AMD drivers to the latest version for the best performance.

The game won't launch — what should I try?

Check that extraction completed and your PC meets the system requirements, including Version 11. Note any error message before choosing a fix. If it identifies a missing runtime, install the required DirectX components or Microsoft Visual C++ Redistributable from Microsoft.

My antivirus is blocking the game — is it safe?

A warning needs to be investigated; the download source alone cannot confirm that a file is safe. Keep your security software enabled and review the detection details. Do not run or restore a flagged file unless you have verified that it is a false positive. If you are unsure, leave it quarantined.

Need more help? Browse our FAQ & Troubleshooting Guide for solutions to common issues.
Looking for something else? Explore all games on SteamUnlocked →
Saved to My Library View Library